Crispr, the gene-editing tool transforming biotechnology, is showing even greater promise for treating genetic disease thanks to two developments unveiled yesterday.
The advances were published by two teams of scientists from Massachusetts Institute of Technology and Harvard University, working together at the Broad Institute, their joint facility.
One of the groups has adapted Crispr to make it easier to change individual chemical “letters” of DNA in genetic code, rather than inserting or deleting whole genes. Their tool, described in the journal Nature, is known as base editing and can be likened to using a sharp pencil rather than scissors on the genome.
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