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Babies born with DNA from 3 people in pioneering UK IVF trial

Mitochondrial transfer offers fresh hope to parents at risk of passing on incurable genetic disease to their children
Newcastle University was licensed in 2017 to carry out the trial of mitochondrial transfer with funding from the NHS and Wellcome Trust

Eight healthy babies have been born following mitochondrial transfer, which creates “three-parent” embryos, in the world’s first clinical assessment of the treatment developed to reduce the risk of DNA diseases.

Genetic defects in mitochondrial DNA affect about one baby in 5,000, leading to a wide range of medical problems from muscle atrophy to heart failure and brain disease.

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