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Gates Foundation makes unusual investment in experimental cancer trial

Smart Immune is developing technology it hopes will help patients rebuild their immune systems
Karine Rossignol, Smart Immune chief executive

The Bill & Melinda Gates Foundation is making an unusual investment in a biotech start-up’s experimental cancer trial, hoping that its novel technology will one day allow HIV patients to rebuild their immune systems.

Smart Immune, a French cell therapy company led by three female co-founders, has developed technology to coax stem cells, which have the ability to develop into many different cell types, into becoming immature “progenitor” T-cells in a lab. These are then injected into the body, where they mature into a crucial part of the immune system and learn to differentiate between normal cells and threats.

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